The Science of CBD Part 3

The Science of CBD Part 3

Lets focus today in our part 3 of the series on ailments CBD has been known to help and the Procedure of Extracting CBD from the plant itself.

 

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Chronic Pain

Management of chronic pain is on of the biggest application for which CBD is suited, it works in a several of ways. CBD and other non-THC cannabinoids found in hemp flower-bud extracts as well as the terpenes  work together to help block pain-conducting nerve impulses, which reduces your perception of pain.

 Stimulation of CB₁ in the brain increases dopamine, which helps counteracts pain. Just as importantly, these same chemical substances reduce inflammation, the the primary cause behind all pain, which allows healing to occur.

CBD and other cannabinoids also reduce pain by affecting endorphins, our bodies on natural pain killing chemicals that naturally suppress pain. Unlike opioids (heroin, narcotic opioids), which mimic endorphins and ultimately suppress natural endorphins ( these put the bodies natural opioid receptors to sleep), where cannabinoids adjust endorphins and help the body to make more of the good feeling chemicals our bodies are naturally designed to produce.

This means, in effect, that CBD and cannabinoids increase natural endorphins. So instead of causing dependence and addiction like opioids, CBD and other cannabinoids actually stimulate the bodies natural defense mechanisms to help reduce pain. This effect works so well in face CBD has proven to be a valuable tool for countering narcotic and cocaine addiction. From a medicinal view, the fact that CBD has the potential to relieve pain without causing euphoria, intoxication, or addiction makes it a very promising therapeutic option compared to todays standard narcotics. Actually it has great potential for being a partial solution to the current opioid epidemic.

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Immune dysfunction + chronic illness

CBD and other chemical substances in hemp flower-bud extracts are strong immune system modulators. This means they control inflammation throughout the body, and also fine-tune the immune system for optimal performance. This combined with CBD’s ability to ease pain and anxiety make it an ideal consideration for illnesses associated with immune dysfunction, including fibromyalgia, chronic fatigue syndrome, chronic Lyme disease, and autoimmune illnesses.

Gut dysfunction

The immunomodulation benefits of CBD and cannabinoids extend to the GI tract. CBD may have value in treating inflammatory bowel diseases, including Crohn’s disease and ulcerative colitis, but that value is still being defined by clinical studies.

Cancer symptoms

The wide range of benefits associated with cannabis have garnered interest for use in cancer therapy. Research suggests that cannabinoids, including CBD, may have anti-tumor effects. While this is not enough to define cannabis as a treatment for cancer, it does make it attractive as a complement to other therapies, for both reducing symptoms and possibly enhancing the effects of anticancer drugs.

Additional health concerns

The benefits of CBD and other non-THC cannabinoids don’t stop there. Terpenes and the wide spectrum of other chemical compounds found in hemp flower-bud extracts provide potent anti-inflammatory and antioxidant properties. And like most other herbs, hemp flower-bud extracts have been associated with antimicrobial properties, though cannabis doesn’t appear to be as strong an antimicrobial as many other herbs.

What’s the difference between hemp oil and hemp oil with CBD?

This is a common source of confusion. Many people see hemp oil on grocery store shelves and assume or wonder if it contains CBD and other cannabinoids. Adding to the confusion, CBD products are often sold as hemp oil, and CBD oil is often mixed with hemp oil.

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But make no mistake, hemp oil and hemp oil with CBD (or CBD oil) are not the same. The hemp oil you might see on grocery store shelves is made by cold pressing hemp seeds. It’s high in omega-3 fatty acids and other beneficial fatty acids, but hemp oil found in the grocery store does not contain significant amounts of cannabinoids including THC or CBD. While hemp oil is a healthful option for a salad dressing, it has no medicinal value by itself.

Cannabinoids, including CBD in hemp and THC in marijuana, are most highly concentrated in the flower buds, not the seeds. These chemical components of the plant must be extracted from the flower buds to be useful.

What is the best CBD extraction method?

For medicinal use, cannabinoids are extracted from hemp and concentrated into a thick oil that, when ingested, elevates blood levels of cannabinoids for a more sustained period of time. (That’s compared to inhaling vaporized marijuana, where THC dissipates from blood quickly, making it ideal for recreational use.)

CBD oil from hemp contains CBD and other cannabinoids, along with terpenes and other chemical components. It contains only trace amounts of THC (<0.3%).

The four main methods of CBD extraction

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• Chemical extraction: The most common method, chemical extraction uses alcohol or hexane as solvents. The solvent is dried off, leaving the dense oil — and possibly harmful residual solvents — behind.
• CO₂ extraction: A newer method, CO₂ extraction is done without using chemical solvents. Instead, it uses carbon dioxide to extract the full range of chemical components from the flower buds and then distill them into dense CBD oil.
• Vapor Distillation™: Also sometimes called thermal extraction, vapor distillation uses hot air to safely vaporize the full spectrum of chemical components at high concentration from the buds, and then the vapor is distilled into CBD oil. This method also activates the cannabinoids by removing an extra carboxyl ring from their molecular chain (a chemical reaction called decarboxylation), enabling them to interact directly with CB receptors for maximal medicinal value.
  
  
  I believe vapor distillation is the best method for obtaining the full range of activated chemical compounds from the cannabis plant. This method preserves the terpenes, which are beneficial on their own, and also enhance the properties of CBD via the entourage effect.
• Lipid-based extraction: This method uses fats such as organic coconut oil to absorb and encapsulate the plant’s chemical compounds. The upsides of lipid-based extraction are that the fat helps make the CBD more bioavailable (easy to absorb), and there are no harsh solvents used. The downside: you won’t get a full spectrum of compounds like you would with vapor distillation or CO₂ extraction.